The landscape of somatic copy-number alteration across human cancers

Rameen Beroukhim, Craig H. Mermel, Dale Porter, +59

Nature

Somatic VariantTumor HeterogeneityMedicinePathologySomatic Copy-number Alteration +5

Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion

Akira Orimo, Piyush B. Gupta, Dennis C. Sgroi, +6

Cell

Breast OncologyMedicinePathologyFibroblast Growth FactorBreast Cancer +8

Genes that mediate breast cancer metastasis to lung

Andy J. Minn, Gaorav P. Gupta, Peter M. Siegel, +7

Nature

Breast Cancer MetastasisMedicineBreast CancerCancer GeneticsCancer Biology +3

A multigenic program mediating breast cancer metastasis to bone

Yibin Kang, Peter M. Siegel, Weiping Shu, +5

Cancer Cell

Breast OncologyBreast CancerSystems BiologyMedicineTumor Microenvironment

Endogenous human microRNAs that suppress breast cancer metastasis

Sohail F. Tavazoie, Claudio R. Alarcón, Thórdur Óskarsson, +5

Nature

Breast Cancer MetastasisBreast CancerSmall RnaMicrorna DetectionMedicine +3

The microRNAs miR-373 and miR-520c promote tumour invasion and metastasis

Qihong Huang, Kiranmai Gumireddy, Mariëtte Schrier, +13

Nature Cell Biology

OncologyMedicineMicrorna DetectionSmall RnaRadiation Oncology +5

A microRNA regulon that mediates endothelial recruitment and metastasis by cancer cells

Kim J. Png, Nils Halberg, Mitsukuni Yoshida, +1

Nature

Endothelial Cell PathobiologyAngiogenesisMedicineCancer Cell BiologyVascular Biology +9

GOLPH3 Bridges Phosphatidylinositol-4- Phosphate and Actomyosin to Stretch and Shape the Golgi to Promote Budding

Holly C. Dippold, Michelle M. Ng, Suzette Farber-Katz, +12

Cell

BiologyGolgi ApparatusSignal TransductionCell SignalingNatural Sciences +10

The gene expression signatures of melanoma progression

Christopher M. Haqq, Mehdi Nosrati, Daniel Sudilovsky, +11

Proceedings of the National Academy of Sciences

Tumor BiologyMelanoma MetastasesGene Expression SignaturesMedicineMelanoma +13

Convergent Multi-miRNA Targeting of ApoE Drives LRP1/LRP8-Dependent Melanoma Metastasis and Angiogenesis

Nora Pencheva, Hien Tran, Colin G. Buss, +4

Cell

MedicineMelanomaConvergent Multi-mirna TargetingMicrorna DetectionRadiation Oncology +3