N-Phenyl indole derivatives as AT1 antagonists with anti-hypertension activities: Design, synthesis and biological evaluation

Hypertension: Pathophysiology, Diagnosis, and Management

William B. White · JAMA · 1991 · 948 citations

Medicine, Cardiology, Clinical Sciences +12

Nonpeptide angiotensin II receptor antagonists. VII. Cellular and biochemical pharmacology of DuP 753, an orally active antihypertensive agent.

Andrew T. Chiu, Dale E. McCall, William A. Price et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 317 citations

Medicine, Medicinal Chemistry, Pharmacology +13

6-Substituted benzimidazoles as new nonpeptide angiotensin II receptor antagonists: synthesis, biological activity, and structure-activity relationships

Uwe J. Ries, Gerhard Mihm, Berthold Narr et al. · Journal of Medicinal Chemistry · 1993 · 203 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Angiotensin II type I receptor antagonist inhibits the gene expression of transforming growth factor-beta 1 and extracellular matrix in cardiac and vascular tissues of hypertensive rats.

S Kim, Kensuke Ohta, Akinori Hamaguchi et al. · Journal of Pharmacology and Experimental Therapeutics · 1995 · 148 citations

Life Sciences, Molecular Biology, Pharmacology +16

Iron-Catalyzed Cross-Coupling of <i>N</i>-Heterocyclic Chlorides and Bromides with Arylmagnesium Reagents

Olesya M. Kuzmina, Andreas K. Steib, Dietmar Flubacher et al. · Organic Letters · 2012 · 92 citations

Natural Sciences, Chemistry, Catalysis +10