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Potent acid inhibition by vonoprazan in comparison with esomeprazole, with reference to<scp>CYP</scp>2C19 genotype

DOIFull Paper Access

247

Citations

45

References

2016

Year

Takuma Kagami, Shu Sahara, H. Ichikawa, Takahiro Uotani, Mihoko Yamade, Mitsushige Sugimoto, Yasushi Hamaya, Moriya Iwaizumi, Satoshi Osawa, Ken Sugimoto,
Alimentary Pharmacology & Therapeutics

Abstract

Vonoprazan 20 mg b.d. inhibits acid irrespective of CYP2C19 genotype, more potently than esomeprazole 20 mg b.d., pH 4 and 5 holding time ratios reached 100% and 99%, respectively.

References

YearCitations

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