Transforming growth factor-beta 1 produced by vascular smooth muscle cells predicts fibrosis in the gastrocnemius of patients with peripheral artery disease - Concepedia

Concepedia

Publication | Open Access

Transforming growth factor-beta 1 produced by vascular smooth muscle cells predicts fibrosis in the gastrocnemius of patients with peripheral artery disease

DOI Full Paper Access

60

Citations

36

References

2016

Year

Duy M. Ha, Lauren C. Carpenter, Panagiotis Koutakis, Stanley A. Swanson, Zhen Zhu, Mina Hanna, Holly DeSpiegelaere, Iraklis I. Pipinos, George P. Casale

Journal of Translational Medicine

Abstract

Our findings support a progressive fibrosis in the gastrocnemius of PAD patients that is caused by elevated TGF-β1 production in the SMC of microvessels in response to tissue hypoxia.

References

	Year	Citations

Page 1