Concepedia

Intramyocardial stem cell injection: go(ne) with the flow

F. van den Akker, Dries Feyen, Patricia van den Hoogen, Linda W. van Laake, Esther C. M. van Eeuwijk, Imo E. Hoefer, Gerard Pasterkamp, Steven A. J. Chamuleau, Paul F. Gründeman, Pieter A. Doevendans,

European Heart Journal · 2016 · 82 citations · 4 references

DOIFull text

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Concepts

Abstract

In this study, we visualize the real-time dynamics of intramyocardial stem-cell injections. This shows a massive, immediate wash-out via venous drainage, accounting for the low retention. The use of carriers reduces this outflow.

References

4

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Toby Freyman, Glenn M. Polin, Hashim Osman et al. · European Heart Journal · 2006 · 612 citations · Full text

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Transendocardial cell injection is not superior to intracoronary infusion in a porcine model of ischaemic cardiomyopathy: a study on delivery efficiency

T. I. G. van der Spoel, Krijn R. Vrijsen, Stefan Koudstaal et al. · Journal of Cellular and Molecular Medicine · 2012 · 51 citations · Full text

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First experience with remote left ventricular mapping and transendocardial cell injection with a novel integrated magnetic navigation-guided electromechanical mapping system.

Emerson C. Perin, Guilherme V. Silva, Marlos R. Fernandes et al. · PubMed · 2007 · 19 citations

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Assessment of collateral artery function and growth in a pig model of stepwise coronary occlusion

Daphne de Groot, Sebastian Grundmann, Leo Timmers et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2010 · 13 citations

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