Leo Timmers

Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

Ruenn Chai Lai, Fatih Arslan, May May Lee et al. · Stem Cell Research · 2010 · 2.2K citations

Cell Physiology, Protein Secretion, Immunology +7

Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury

Fatih Arslan, Ruenn Chai Lai, Mirjam B. Smeets et al. · Stem Cell Research · 2013 · 1.1K citations

Regenerative Medicine, Medicine, Adult Stem Cell +13

Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium

Leo Timmers, Sai Kiang Lim, Fatih Arslan et al. · Stem Cell Research · 2008 · 613 citations

Regenerative Medicine, Tissue Engineering, Medicine +9

Exenatide Reduces Infarct Size and Improves Cardiac Function in a Porcine Model of Ischemia and Reperfusion Injury

Leo Timmers, José P.S. Henriques, Dominique P.V. de Kleijn et al. · Journal of the American College of Cardiology · 2009 · 462 citations

Porcine Model, Thrombosis, Heart Failure +11

Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction

Leo Timmers, Sai Kiang Lim, Imo E. Hoefer et al. · Stem Cell Research · 2011 · 423 citations

Regenerative Medicine, Cardiac Function, Medicine +11