Concepedia

Elevated circulating stearic acid leads to a major lipotoxic effect on mouse pancreatic beta cells in hyperlipidaemia via a miR-34a-5p-mediated PERK/p53-dependent pathway

Huimin Lu, Liuyi Hao, Songtao Li, Lin Lv, Yang Chen, Hongli Cui, Tianqi Zi, Xia Chu, Lixin Na, Changhao Sun

Diabetologia · 2016 · 100 citations · 40 references

DOIFull text

Open access

Concepts

References

40

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

Laura Listenberger, Xianlin Han, Sarah E. Lewis et al. · Proceedings of the National Academy of Sciences · 2003 · 2.1K citations · Full text

, , +17

[19] Receptor-mediated endocytosis of low-density lipoprotein in cultured cells

Joseph L. Goldstein, Sandip K. Basu, Michael S. Brown · Methods in enzymology on CD-ROM/Methods in enzymology · 1983 · 1.6K citations

, , +14

The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2

Baofeng Yang, Huixian Lin, Jiening Xiao et al. · Nature Medicine · 2007 · 1.1K citations

, , +12

Alterations in MicroRNA Expression Contribute to Fatty Acid–Induced Pancreatic β-Cell Dysfunction

Pascal Lovis, E. Roggli, D. Ross Laybutt et al. · Diabetes · 2008 · 360 citations · Full text

, , +17

Involvement of MicroRNAs in the Cytotoxic Effects Exerted by Proinflammatory Cytokines on Pancreatic β-Cells

E. Roggli, Aurore Britan, Sonia Gattesco et al. · Diabetes · 2010 · 317 citations · Full text

, , +17