CD200Fc reduces TLR4-mediated inflammatory responses in LPS-induced rat primary microglial cells via inhibition of the NF-κB pathway

Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction

Katherine A. Fitzgerald, Eva M. Pålsson‐McDermott, Andrew Bowie et al. · Nature · 2001 · 1.3K citations

Life Sciences, Immunology, Molecular Biology +12

mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging

Matthew G. Frank, Ruth M. Barrientos, Joseph C. Biedenkapp et al. · Neurobiology of Aging · 2005 · 332 citations

Life Sciences, Neurobiology, Neuroscience +17

Decreased expression of CD200 and CD200 receptor in Alzheimer's disease: A potential mechanism leading to chronic inflammation

Douglas G. Walker, Jessica Dalsing-Hernandez, Nicole A. Campbell et al. · Experimental Neurology · 2008 · 272 citations · Full text

Life Sciences, Neurobiology, Neuroscience +13

Constitutive Retinal CD200 Expression Regulates Resident Microglia and Activation State of Inflammatory Cells during Experimental Autoimmune Uveoretinitis

Cathryn Broderick, Robert M. Hoek, John V. Forrester et al. · American Journal Of Pathology · 2002 · 218 citations · Full text

Medicine, Immunology, Ophthalmology +16

Distribution of the Immune Inhibitory Molecules CD200 and CD200R in the Normal Central Nervous System and Multiple Sclerosis Lesions Suggests Neuron-Glia and Glia-Glia Interactions

Nathalie Koning, Dick F. Swaab, Robert M. Hoek et al. · Journal of Neuropathology & Experimental Neurology · 2009 · 190 citations

Life Sciences, Neurology, Neuroscience +17