Concepedia

Construction and preclinical evaluation of mmCT, a novel mutant cholera toxin adjuvant that can be efficiently produced in genetically manipulated Vibrio cholerae

Michael Lebens, Manuela Terrinoni, Stefán Karlsson, Maximilian Larena, Tobias Gustafsson‐Hedberg, Susanne Källgård, Erik Nygren, Jan Holmgren

Vaccine · 2016 · 40 citations · 30 references

DOI

Concepts

References

30

Mechanisms of Action of Adjuvants

Sunita Awate, Lorne A. Babiuk, George Mutwiri · Frontiers in Immunology · 2013 · 730 citations · Full text

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Protein Disulfide Isomerase Acts as a Redox-Dependent Chaperone to Unfold Cholera Toxin

Billy Tsai, Chiara Rodighiero, Wayne I. Lencer et al. · Cell · 2001 · 476 citations · Full text

, , +16

Generalized systemic and mucosal immunity in mice after mucosal stimulation with cholera toxin.

Charles O. Elson, W Ealding · The Journal of Immunology · 1984 · 445 citations

, , +15

Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens.

Nils Lycke, Jan Holmgren · PubMed · 1986 · 428 citations · Full text

, , +16

The nucleotide sequence of pACYC184

Ronald E. Rose · Nucleic Acids Research · 1988 · 408 citations · Full text

, , +12