Concepedia

The dimerization interfaces formed between the DNA binding domains of RXR, RAR and TR determine the binding specificity and polarity of the full-length receptors to direct repeats.

Christina Zechel, Xi-Qiang Shen, Jake Y. Chen, Chen Zp, Pascal Chambon, Hinrich Gronemeyer

The EMBO Journal · 1994 · 251 citations · 39 references

DOIFull text

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Concepts

References

39

Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors

Steven A. Kliewer, Kazuhiko Umesono, Daniel J. Noonan et al. · Nature · 1992 · 1.7K citations · Full text

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Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

Ben F. Luisi, Wei Xu, Zbyszek Otwinowski et al. · Nature · 1991 · 1.5K citations

, , +8

Determinants of target gene specificity for steroid/thyroid hormone receptors

Kazuhiko Umesono, Ronald M. Evans · Cell · 1989 · 950 citations

, , +6

Fatty acids and retinoids control lipid metabolism through activation of peroxisome proliferator-activated receptor-retinoid X receptor heterodimers.

H. Keller, C Dreyer, Jeffrey A. Medin et al. · Proceedings of the National Academy of Sciences · 1993 · 948 citations

, , +15

Cloning of murine α and β retinoic acid receptors and a novel receptor γ predominantly expressed in skin

Arthur Zelent, Andrée Krust, Martin Petkovich et al. · Nature · 1989 · 801 citations

, , +11