The effects of small doses of megestrol acetate on the cervical mucus.

Abstract

17 parous women aged 19-28 years received continuous microdoses (.5 and .25 mg) of oral megestrol acetate. Tests for cervical mucus effects of the drug were done during control and treated cycles. The drug decreased cervical secretion increased dry matter content and elasticity and increased potassium. pH and sodium concentration were not affected. Sperm penetration of the cervical mucus was reduced in treated cycles.