Inhibition of heme oxygenase-1 enhances the chemosensitivity of laryngeal squamous cell cancer Hep-2 cells to cisplatin

Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia

Michael A. Barry, Catherine A. Behnke, Alan Eastman · Biochemical Pharmacology · 1990 · 879 citations

Life Sciences, Oncology, Pharmacology +14

Phase III Study Comparing Cisplatin Plus Fluorouracil to Paclitaxel, Cisplatin, and Fluorouracil Induction Chemotherapy Followed by Chemoradiotherapy in Locally Advanced Head and Neck Cancer

Ricardo Hitt, Antonio López–Pousa, Javier Martínez‐Trufero et al. · Journal of Clinical Oncology · 2005 · 454 citations

Medicine, Oncology, Radiation Oncology +15

Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells

C. Marzano, Valentina Gandin, Alessandra Folda et al. · Free Radical Biology and Medicine · 2006 · 415 citations

Life Sciences, Oncology, Pharmacology +15

Apoptosis by cisplatin requires p53 mediated p38α MAPK activation through ROS generation

Paloma Bragado, Alejandro Armesilla, Augusto Silva et al. · APOPTOSIS · 2007 · 370 citations

Life Sciences, Cell Biology, Oncology +14

Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction

Yukiko Gotoh, Jonathan A. Cooper · Journal of Biological Chemistry · 1998 · 355 citations · Full text

Life Sciences, Cell Biology, Pathobiology +14