Indian Journal of Critical Care Medicine · 2015 · 32 citations · 18 references
PharmacyPharmacologyPharmacotherapyPesticide ToxicologyPharmaceutical ToxicologyPoisoning ManagementAcute Pesticide PoisoningAluminum ToxicityAluminum ToxicologyPesticide PoisoningAntidote MechanismsCytochrome Oxidase InhibitionHypoxiaHypoxia FormationIntravenous Lipid EmulsionLipid Emulsion FormulationsPesticide Poisoning Management
Aluminum phosphide (ALP) is a cheap, easily available agricultural pesticide which causes lethal poisoning by liberation of phosphine and inhibition of cytochrome c oxidase thereby leading to cellular hypoxia. Although there is no known specific antidote, clinical trials are still going on. We present here two cases of ALP poisoning who were successfully managed by treatment with lipid emulsion and intravenous magnesium sulfate.
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Managing aluminum phosphide poisonings
Mohan Gurjar, ArvindK Baronia, Afzal Azim et al. · Journal of Emergencies Trauma and Shock · 2011 · 198 citations · Full text