Publication | Open Access

Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1-substituted-4-(4-methoxybenzyl)phthalazine derivatives

Molecular DockingMedicinal ChemistryBiochemistryMedicineNatural SciencesVegfr-2 InhibitorsRational Drug DesignBinding AffinityActive SiteDrug DevelopmentChemical BiologyPharmacologyMolecular ModelingDrug Discovery