Concepedia

Effectiveness and mode of action of a combination therapy for heterotopic ossification with a retinoid agonist and an anti-inflammatory agent

Sayantani Sinha, Kenta Uchibe, Yu Usami, Maurizio Pacifici, Masahiro Iwamoto

Bone · 2016 · 36 citations · 57 references

DOI

Concepts

References

57

Inhibition of osteoblastogenesis and promotion of apoptosis of osteoblasts and osteocytes by glucocorticoids. Potential mechanisms of their deleterious effects on bone.

Robert S. Weinstein, R L Jilka, A. M. Parfitt et al. · Journal of Clinical Investigation · 1998 · 1.8K citations · Full text

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A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

Eileen M. Shore, Meiqi Xu, George Feldman et al. · Nature Genetics · 2006 · 1.2K citations

, , +11

The Retinoids-Biology, Chemistry and Medicine

George Wolf · American Journal of Clinical Nutrition · 1994 · 1K citations

, , +3

BMP type I receptor inhibition reduces heterotopic ossification

Paul B. Yu, Donna Y. Deng, Carol Lai et al. · Nature Medicine · 2008 · 628 citations · Full text

, , +12

A Clinical Perspective on Common Forms of Acquired Heterotopic Ossification

Douglas E. Garland · Clinical Orthopaedics and Related Research · 1991 · 446 citations

, , +12