Concepedia

Aldehydes with high and low toxicities inactivate cells by damaging distinct cellular targets

Ming-Zhang Xie, Mahmoud I. Shoulkamy, Amir M.H. Salem, Shunya Oba, Mizuki Goda, Toshiaki Nakano, Hiroshi Ide

Mutation research. Fundamental and molecular mechanisms of mutagenesis · 2016 · 97 citations · 28 references

DOI

Concepts

References

28

Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis.

Owen W. Griffith · Journal of Biological Chemistry · 1982 · 701 citations · Full text

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Fancd2 counteracts the toxic effects of naturally produced aldehydes in mice

Frédéric Langevin, Gerry P. Crossan, Iván V. Rosado et al. · Nature · 2011 · 513 citations

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The Fanconi Anaemia Gene FANCC Promotes Homologous Recombination and Error-Prone DNA Repair

Wojciech Niedźwiedź, Georgina Mosedale, Mark Johnson et al. · Molecular Cell · 2004 · 311 citations · Full text

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ERCC1-XPF Endonuclease Facilitates DNA Double-Strand Break Repair

Anwaar Ahmad, Andria R. Robinson, Anette Duensing et al. · Molecular and Cellular Biology · 2008 · 297 citations · Full text

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Formaldehyde catabolism is essential in cells deficient for the Fanconi anemia DNA-repair pathway

Iván V. Rosado, Frédéric Langevin, Gerry P. Crossan et al. · Nature Structural & Molecular Biology · 2011 · 193 citations

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