Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015

Moon‐Woo Seong, So Yeon Kim, Victor M. Corman, Taek Soo Kim, Sung Im Cho, Man Jin Kim, Seung Jun Lee, Soo Hyun Seo, Ji Soo Ahn, Byeong Su Yu,

Emerging infectious diseases · 2015 · 38 citations · 15 references

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Abstract

During the 2015 Middle East respiratory syndrome coronavirus outbreak in South Korea, we sequenced full viral genomes of strains isolated from 4 patients early and late during infection. Patients represented at least 4 generations of transmission. We found no evidence of changes in the evolutionary rate and no reason to suspect adaptive changes in viral proteins.

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