International Journal of Clinical Practice · 1997 · 13 citations · 2 references
MedicineDermatologyNephrologyDermatopathologyHistopathologyHypersensitivityDrug-induced Skin ReactionsPeptic Ulcer DiseasePeptic Ulcer PharmacotherapyUlcer ManagementDrug-induced PurpuraHenoch-schönlein PurpuraHistamine-2 Receptor Antagonist TherapyImpaired Kidney FunctionPeptic Ulcer Disease PathophysiologyPeptic Ulcer PathophysiologyVasculitic Inflammation
Ranitidine is one of the widely prescribed H2 receptor antagonists in the treatment of peptic ulcer. It is well tolerated and has few side-effects. Vasculitic rash occurring in association with ranitidine has been described. We report a case of a 39-year-old man who developed a purpuric rash, polyarthritis, abdominal pain, melaena and impaired renal function characteristic of Henoch-Schonlein purpura, following treatment with ranitidine.
2
Florabel G. Mullick, Hugh A. McAllister, Bernard M. Wagner et al. · Human Pathology · 1979 · 152 citations
Rash mediated by immune complexes associated with ranitidine treatment
N.Y. Haboubi, P Asquith · BMJ · 1988 · 15 citations · Full text
Medicine, Dermatology, Pharmacology +11