Reduction in Na+ current by angiotensin II is mediated by PKCα in mouse and human-induced pluripotent stem cell–derived cardiomyocytes

PKC-α regulates cardiac contractility and propensity toward heart failure

Julian C. Braz, Kimberly N. Gregory, Anand Pathak et al. · Nature Medicine · 2004 · 593 citations

Medicine, Cardiology, Physiology +12

Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling

Pierre Paradis, Nassim Dali‐Youcef, François Paradis et al. · Proceedings of the National Academy of Sciences · 2000 · 383 citations

Life Sciences, Pharmacology, Physiology +10

Mice with Cardiac-Restricted Angiotensin-Converting Enzyme (ACE) Have Atrial Enlargement, Cardiac Arrhythmia, and Sudden Death

Hong Xiao, Sébastien Fuchs, Duncan J. Campbell et al. · American Journal Of Pathology · 2004 · 259 citations · Full text

Medicine, Cardiology, Physiology +7

Cardiac-specific overexpression of AT1 receptor mutant lacking G q/G i coupling causes hypertrophy and bradycardia in transgenic mice

Peiyong Zhai · Journal of Clinical Investigation · 2005 · 167 citations · Full text

Life Sciences, Cardiology, Molecular Biology +14

Gender-Based Differences in Cardiac Repolarization in Mouse Ventricle

Véronique Trépanier‐Boulay, Chantale St-Michel, Annie Tremblay et al. · Circulation Research · 2001 · 158 citations · Full text

Medicine, Cardiology, Physiology +17