Concepedia

Disposition of Valproic Acid in Maternal, Fetal, and Newborn Sheep I: Placental Transfer, Plasma Protein Binding, and Clearance

Sanjeev Kumar, K W Riggs, F S Abbott, Dan Rurak

Drug Metabolism and Disposition · 2000 · 23 citations · 33 references

DOI

Concepts

References

33

A physiological approach to hepatic drug clearance

G. Wilkinson, David G. Shand · Clinical Pharmacology & Therapeutics · 1975 · 1.9K citations

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Valproic acid. A reappraisal of its pharmacological properties and clinical efficacy in epilepsy.

Rick Davis, David H. Peters, Donna McTavish · PubMed · 1994 · 294 citations

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Valproic Acid

Rick D. Davis, David H. Peters, Donna McTavish · Drugs · 1994 · 238 citations

, , +14

Valproic acid and its metabolites: placental transfer, neonatal pharmacokinetics, transfer via mother's milk and clinical status in neonates of epileptic mothers.

Heinz Nau, D. Rating, S. Koch et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 231 citations

, , +17

Valproic acid in the perinatal period: Decreased maternal serum protein binding results in fetal accumulation and neonatal displacement of the drug and some metabolites

Heinz Nau, H Helge, W. A. P. Luck · The Journal of Pediatrics · 1984 · 110 citations

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