Publication | Closed Access
Nose to brain delivery of astaxanthin-loaded solid lipid nanoparticles: fabrication, radio labeling, optimization and biological studies
74
Citations
27
References
2016
Year
NanoparticlesEngineeringRadio LabelingBiofabricationBiomedical EngineeringConventional Dosage FormRedox BiologyOxidative StressNanomedicineTherapeutic NanomaterialsToxicologyBrain DeliveryDrug Delivery SystemCell-based Drug DeliveryRedox SignalingAstaxanthin NanoformulationBiochemistryNeuroprotectionBiological StudiesReactive Oxygen SpeciePharmacologyPharmaceutical NanotechnologyNano-drug DeliveryMedicine
Astaxanthin nanoformulation was found appropriate in all measures with strong antioxidant activity against H<sub>2</sub>O<sub>2</sub>induced oxidative stress in PC12 cells. Biodistribution and brain delivery was also found to be superior to conventional dosage form.
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