Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway

Cancer statistics, 2015

Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal · CA A Cancer Journal for Clinicians · 2015 · 11.9K citations · Full text

Medicine, Oncology, Cancer Epidemiology +16

The expanding role of mitochondria in apoptosis.

X. Wang · PubMed · 2001 · 2.4K citations

Life Sciences, Cell Biology, Molecular Biology +14

Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism

Dong‐Mei Ren, Nicole Villeneuve, Tao Jiang et al. · Proceedings of the National Academy of Sciences · 2011 · 652 citations

Medicine, Oncology, Pharmacology +14

Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2′,5,6′-Tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymol

Victor Kuete, Patricia Djuissi Tchakam, Benjamin Wiench et al. · Phytomedicine · 2013 · 100 citations

Pharmacy, Pharmacology, Toxicology +12

Brusatol-mediated induction of leukemic cell differentiation and G1 arrest is associated with down-regulation of c-myc

Eugenia Mata‐Greenwood, Muriel Cuendet, Dorie Sher et al. · Leukemia · 2002 · 83 citations

Medicine, Molecular Biology, Oncology +16