Influence of ApoE and FABP2 polymorphisms and environmental factors in the susceptibility to gallstone disease

Abstract

These data suggest that the Apo E4 allele could confer genetic susceptibility for the development of GSD among the Mexican population. The Ala54Thr polymorphism of FABP2 was associated with high triglycerides levels, but not to GSD; suggesting that environmental factors modulate such susceptibility.