Concepedia

Which Route of Tranexamic Acid Administration is More Effective to Reduce Blood Loss Following Total Knee Arthroplasty?

Sohrab Keyhani, Ali Akbar Esmailiejah, Mohammad Reza Abbasian, Farshad Safdari

PubMed · 2016 · 51 citations · 21 references

Full text

Open access

Abstract

Tranexamic acid is a useful antifibrinolytic drug to reduce postoperative blood loss, Hb drop, and rate of blood transfusion in patients undergoing total knee arthroplasty. The route of tranexamic acid administration did not affect the efficacy and safety.

References

21

An Analysis of Blood Management in Patients Having a Total Hip or Knee Arthroplasty*

Benjamin E. Bierbaum, John J. Callaghan, J O Galante et al. · Journal of Bone and Joint Surgery · 1999 · 985 citations

Topical Application of Tranexamic Acid Reduces Postoperative Blood Loss in Total Knee Arthroplasty

Jean Wong, Amir Abrishami, Hossam El Beheiry et al. · Journal of Bone and Joint Surgery · 2010 · 482 citations

Tranexamic acid decreases external blood loss but not hidden blood loss in total knee replacement

Lars Good, Edward L. Peterson, B. Lisander · British Journal of Anaesthesia · 2003 · 448 citations · Full text

, , +6

Tranexamic acid use and postoperative outcomes in patients undergoing total hip or knee arthroplasty in the United States: retrospective analysis of effectiveness and safety

Jashvant Poeran, Rehana Rasul, Suzuko Suzuki et al. · BMJ · 2014 · 448 citations · Full text

Efficacy of aminocaproic, tranexamic acids in the control of bleeding during total knee replacement: a randomized clinical trial

Miguel Ángel Camarasa, G. Ollé, Mateu Serra‐Prat et al. · British Journal of Anaesthesia · 2006 · 263 citations · Full text

, , +4