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Elevation of serum erythropoietin after subtotal parathyroidectomy in chronic haemodialysis patients

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1992

Year

Abstract

After successful subtotal parathyroidectomy (PTX) in 10 chronic haemodialysis patients, significant elevation of Epo was observed, from 48.4± 17.8 mU/ml(M ±SEM) at preoperative state to 103.3±34.7mU/ml at 6 h and 163.4±50.2mU/ml at 12 h after PTX. Significant reductions in both PTH-m and ionized calcium (iCa) were confirmed. Since Epo did not increase in the cases with an inadequate PTX and ovariectomy, an abrupt reduction in PTH with a decrease in iCa may play some role in the elevation of Epo.