Journal of Bone and Joint Surgery - British Volume · 1996 · 18 citations · 7 references
MedicineOrthopaedic SurgeryOrthopedic SurgeryHemostasisJoint Replacement SurgeryOrthopedicsAnticoagulant TherapyAnticoagulation TherapyDeep Vein ThrombosisPulmonary EmbolismThromboembolic DiseaseVenous ThromboembolismPerioperative Pulmonary EmbolismPerioperative ThromboprophylaxisPostoperative Pulmonary EmbolismPostoperative ThromboprophylaxisSurgery-associated Venous ThromboembolismSurgical Patient ThromboprophylaxisThromboprophylaxis In Orthopedic SurgeryWarfarin Dose Optimization
We randomised 250 patients undergoing unilateral, elective hip arthroplasty for osteoarthritis to receive either a cemented or a non-cemented Mallory Head prosthesis. Aspirin was used as prophylaxis against thromboembolism during the first half of the study and adjusted-dose warfarin during the second half. Postoperatively, all patients were asked to have bilateral venography and 80% agreed. All were evaluated clinically for pulmonary embolism. There was no difference in the frequency of deep-venous thrombosis between the two groups (50% cemented nu 47% non-cemented, p = 0.73; 95% CI of the difference -13.6% to 19.3%). Three of the 64 patients (5%) in whom venography had demonstrated isolated distal thrombi developed pulmonary emboli.
7
Roentgen Diagnosis of Venous Thrombosis in the Leg
Keith Rabinov · Archives of Surgery · 1972 · 760 citations