Metabolomic and proteomic analysis of serum from preterm infants with necrotising entercolitis and late-onset sepsis

Abstract

No single protein or metabolite was detected in all NEC or LOS cases which was absent from controls; however, several proteins were identified which were associated with disease status. The differing expression of these proteins between diseased infants potentially relates to differing pathophysiology of disease. Thus, it is unlikely a single biomarker exists for NEC and/or LOS.