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Characterization of reactive stroma in prostate cancer: involvement of growth factors, metalloproteinase matrix, sexual hormones receptors and prostatic stem cells

Maurício Moreira da Silva Júnior, Wagner Eduardo Matheus, Patrick Vianna Garcia, Rafael Mamprim Stopiglia, Athanase Billis, Ubirajara Ferreira, Wagner José Fávaro

International braz j urol · 2015 · 21 citations · 19 references

DOIFull text

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Abstract

It can be concluded that RStr may be a predictive marker of Pca progression, since it was associated with increase of growth factors, imbalance of androgen and estrogen receptors and presence of malign prostatic stem cells.

References

19

Proliferative Inflammatory Atrophy of the Prostate

Angelo M. De Marzo, Valérie Marchi, Jonathan I. Epstein et al. · American Journal Of Pathology · 1999 · 866 citations · Full text

Normal Histology of the Prostate

John E. McNeal · The American Journal of Surgical Pathology · 1988 · 667 citations

Binding of c-Myc to chromatin mediates mitogen-induced acetylation of histone H4 and gene activation

Scott R. Frank, Marianne Schroeder, Paula Fernández et al. · Genes & Development · 2001 · 500 citations · Full text

, , +25

REACTIVE STROMA IN PROSTATE CANCER PROGRESSION

Jennifer A. Tuxhorn, Gustavo E. Ayala, David R. Rowley · The Journal of Urology · 2001 · 495 citations

Prostate stem cell antigen (PSCA) expression increases with high gleason score, advanced stage and bone metastasis in prostate cancer

Zhen Gu, George Thomas, Joyce M. Yamashiro et al. · Oncogene · 2000 · 437 citations

, , +10