Evidence for membrane antigen(s) specific for human B lymphoblasts.

Abstract

IgM antibodies against surface antigen(s) of a subpopulation of PHA-induced lymphoblasts have been found in the sera (20%) of infectious mononucleosis patients by indirect immunofluorescent staining. Maximum staining was obtained at 3°C. Evidence is presented that this subpopulation is derived from B lymphocytes. Common antigenic determinants were also present on four human lymphoid cell lines.