Concepedia

Different NT-proBNP circulating levels for different types of cardiac amyloidosis

Federico Perfetto, Franco Bergesio, Elisa Grifoni, Alessia Fabbri, Gabriele Ciuti, Sabrina Frusconi, Paola Angelotti, Valentina Spini, Francesco Cappelli

Journal of Cardiovascular Medicine · 2016 · 34 citations · 20 references

DOI

Abstract

Amyloidogenic light-chain-derived fibrils induce more severe myocardial dysfunction in light-chain amyloidosis than in ATTR, despite similar myocardial infiltration. Thus, the degree of cardiac dysfunction may be related not only to the amount of amyloid deposited, but also to qualitative differences among fibrils.

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