Emotion-Based Decision Making in schizophrenia: evidence from the Iowa Gambling Task

Abstract

The decision making can be defined as the mental process in which a “choice is made after reflecting on the consequences of that choice” (Bechara & Van Der Linden, 2005; Bechara et al., 1997). It is a complex process that involves cognitive as well as emotion-based functions. In fact human beings make fast adaptive decisions in daily life, and that is based on the skill to relate emotion to contextual stimuli in order to anticipate outcomes through activation of emotional states (Bechara et al., 2005). In this regard, the ventromedial prefrontal cortex (VMPFC) has been widely recognized to play a key role in the emotional decision making process. The VMPFC includes the medial part of the orbitofrontal cortex (OFC), the more ventral sectors of the medial prefrontal cortex and the anterior cingulate cortex (Bechara et al., 1997). In particular the OFC, within the VMPFC, is part of a neural system underpinning decision-making and reward-related behaviours which are thought to be linked to social conduct (Rolls, 2000).