Targeting of radiolabeled J591 antibody to PSMA-expressing tumors: optimization of imaging and therapy based on non-linear compartmental modeling

Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature.

Sam S. Chang, Victor E. Reuter, W. D. W. Heston et al. · PubMed · 1999 · 814 citations

Tumor Biology, Urology, Perineural Invasion +11

Monoclonal antibodies to the extracellular domain of prostate-specific membrane antigen also react with tumor vascular endothelium.

He Liu, P. Moy, Sae Kim et al. · PubMed · 1997 · 531 citations

Extracellular Domain, Immunology, Pathology +16

Constitutive and antibody-induced internalization of prostate-specific membrane antigen.

He Liu, A K Rajasekaran, P. Moy et al. · PubMed · 1998 · 447 citations

Urology, Immunology, Endocytic Pathway +12

Phase II Study of Lutetium-177–Labeled Anti-Prostate-Specific Membrane Antigen Monoclonal Antibody J591 for Metastatic Castration-Resistant Prostate Cancer

Scott T. Tagawa, Matthew I. Milowsky, Michael J. Morris et al. · Clinical Cancer Research · 2013 · 414 citations · Full text

⁸⁹Zr-DFO-J591 for ImmunoPET of Prostate-Specific Membrane Antigen Expression In Vivo

Jason P. Holland, Vadim Divilov, Neil H. Bander et al. · Journal of Nuclear Medicine · 2010 · 405 citations · Full text