Pristimerin triggers AIF-dependent programmed necrosis in glioma cells via activation of JNK

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

Takashi Nakagawa, Shigeomi Shimizu, Tetsuya Watanabe et al. · Nature · 2005 · 1.6K citations

Life Sciences, Biochemistry, Cell Biology +13

Mitochondrio‐nuclear translocation of AIF in apoptosis and necrosis

Éric Daugas, Santos A. Susín, Naoufal Zamzami et al. · The FASEB Journal · 2000 · 779 citations

Life Sciences, Cell Biology, Molecular Biology +15

Role of JNK Translocation to Mitochondria Leading to Inhibition of Mitochondria Bioenergetics in Acetaminophen-induced Liver Injury

Naoko Hanawa, Mie Shinohara, Behnam Saberi et al. · Journal of Biological Chemistry · 2008 · 527 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Shikonin circumvents cancer drug resistance by induction of a necroptotic death

Weidong Han, Ling Li, Shuang Qiu et al. · Molecular Cancer Therapeutics · 2007 · 362 citations

Life Sciences, Oncology, Pharmacology +16

Heme induces programmed necrosis on macrophages through autocrine TNF and ROS production

Guilherme B. Fortes, Letícia S. Alves, Rosane de Oliveira et al. · Blood · 2012 · 246 citations · Full text

Life Sciences, Cell Biology, Immunology +15