PubMed · 1992 · 12 citations · 0 references
Animal PhysiologyAscorbic AcidVeterinary PhysiologyAscorbic Acid TherapyAnimal ScienceMedicinePhysiologyHematologyVeterinary ScienceAnimal HealthEducationVeterinary ResearchAcer RubrumToxicologyRed MaplePharmacologyOxidative Stress
Two horses with red maple (Acer rubrum) toxicity responded to treatment with high doses of vitamin C (ascorbic acid), in addition to blood transfusions, and intravenous fluid therapy. The clinical course included Heinz body anemia, marked methemoglobinemia, depression, and evidence of severe tissue anoxia. Clinical recovery was dramatic with stabilization achieved 36 hours following the initiation of ascorbic acid therapy.