Concepedia

Tocilizumab and pregnancy: Four cases of pregnancy in young women with rheumatoid arthritis refractory to anti-TNF biologics with exposure to tocilizumab

Kayoko Kaneko, Maki Sugitani, Mikako Goto, Atsuko Murashima

Modern Rheumatology · 2016 · 23 citations · 7 references

DOIFull text

Open access

Abstract

TCZ may be a good alternative therapy for RA patients with symptoms that are hard to control with TNF blockers who desire to bear children.

References

7

Effect of interleukin-6 receptor inhibition with tocilizumab in patients with rheumatoid arthritis (OPTION study): a double-blind, placebo-controlled, randomised trial

Josef S Smolen, André Beaulieu, Andrea Rubbert‐Roth et al. · The Lancet · 2008 · 1.4K citations

, , +10

IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial

Paul Emery, Edward Keystone, Hans‐Peter Tony et al. · Annals of the Rheumatic Diseases · 2008 · 1.1K citations · Full text

Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

Jun Hashi­moto, N. Miyasaka, Kazuhiko Yamamoto et al. · Annals of the Rheumatic Diseases · 2007 · 739 citations · Full text

Disease activity of rheumatoid arthritis during pregnancy: Results from a nationwide prospective study

Yaël A de Man, Radboud J. E. M. Dolhain, Fleur E. van de Geijn et al. · Arthritis Care & Research · 2008 · 507 citations

, , +18

Association of higher rheumatoid arthritis disease activity during pregnancy with lower birth weight: Results of a national prospective study

Yaël A de Man, Johanna M. W. Hazes, Hugo van der Heide et al. · Arthritis & Rheumatism · 2009 · 349 citations