Nitric oxide downregulates interleukin 1beta (IL-1beta) stimulated IL-6, IL-8, and prostaglandin E2 production by human chondrocytes. - Concepedia

Concepedia

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Nitric oxide downregulates interleukin 1beta (IL-1beta) stimulated IL-6, IL-8, and prostaglandin E2 production by human chondrocytes.

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References

1998

Year

Yves Henrotin, SX Zheng, G Deby, A Labasse, Jean-Michel Crielaard, Jean‐Yves Reginster

Abstract

LPS and IL-1beta stimulated IL-6, IL-8, and PGE2 production are downregulated by endogenously produced NO, which could limit the inflammatory reaction occurring in arthritis.