Aspalathin, a dihydrochalcone <i>C</i>‐glucoside, protects H9c2 cardiomyocytes against high glucose induced shifts in substrate preference and apoptosis

Abstract

Our study provides evidence that ASP increases glucose oxidation and modulates fatty acid utilization producing a favorable substrate shift in H9c2 cardiomyocytes exposed to high glucose. Such a favorable shift will be of importance in the protection of cardiomyocytes in the diabetic heart.