Bioactive Isoquinolinequinone Alkaloids from the South China Sea Nudibranch <i>Jorunna Funebris</i> and Its Sponge-Prey <i>Xestospongia</i> Sp.

Abstract

Five unusual isoquinolinequinones (3, 7-10) were discovered from both two animals, further confirmed their predator-prey relationship. Preliminary bioassay results and structure-activity relationship studies suggested that several isolated compounds were potential to be drug leads.