Sonographic diagnosis of furosemide-induced nephrocalcinosis in newborn infants.

Abstract

In three newborn infants who had received furosemide for a variety of indications, strongly increased echogenicity in the pyramids of the renal medulla was seen on ultrasonography. In one infant the changes were unilateral, the contralateral kidney being nonfunctional because of probable renal artery thrombosis. One infant died and medullary nephrocalcinosis was confirmed post mortem radiologically as well as by computed tomography and anatomic-histologic examination of the kidneys.