Effect of anti-sclerostin therapy and osteogenesis imperfecta on tissue-level properties in growing and adult mice while controlling for tissue age

An improved technique for determining hardness and elastic modulus using load and displacement sensing indentation experiments

W. C. Oliver, George M. Pharr · Journal of materials research/Pratt's guide to venture capital sources · 1992 · 26.6K citations

Natural Sciences, Materials Engineering, Materials Science +16

Romosozumab in Postmenopausal Women with Low Bone Mineral Density

Michael R. McClung, Andreas Grauer, Steven Boonen et al. · New England Journal of Medicine · 2014 · 1.2K citations

Medicine, Endocrinology, Bone Metabolism +12

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis

Xiaodong Li, Michael S. Ominsky, Kelly Warmington et al. · Journal of Bone and Mineral Research · 2008 · 784 citations

Medicine, Biochemistry, Endocrinology +16

Single-dose, placebo-controlled, randomized study of AMG 785, a sclerostin monoclonal antibody

Desmond Padhi, Graham Jang, Brian Stouch et al. · Journal of Bone and Mineral Research · 2010 · 783 citations

Pharmacy, Pharmacokinetics, Pharmacotherapy +17

Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength

Michael S. Ominsky, Fay Vlasseros, Jacquelin Jolette et al. · Journal of Bone and Mineral Research · 2010 · 413 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +17