Concepedia

<i>N</i>,<i>N</i>′-Disubstituted thiourea and urea derivatives: design, synthesis, docking studies and biological evaluation against nitric oxide synthase

Mariem Chayah, M. Encarnación Camacho, María Dora Carriòn, Miguel Á. Gallo, Miguel Romero, Juan Duarte

MedChemComm · 2016 · 20 citations · 19 references

DOIFull text

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Concepts

Abstract

<italic>N</italic>,<italic>N</italic>′-Disubstituted thioureas and ureas as nNOS and iNOS inhibitors were synthesized. Thiourea <bold>4g</bold> was the best inhibitor without eNOS inhibition.

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