Concepedia

Publication | Open Access

Interplay of Matrix Stiffness and c-SRC in Hepatic Fibrosis

DOIFull Paper Access

42

Citations

28

References

2015

Year

Jan Görtzen, Robert Schierwagen, Jeanette Bierwolf, Sabine Klein, Frank Erhard Uschner, Peter F. M. van der Ven, Dieter O. Fürst, Christian P. Strassburg, Wim Laleman, Joerg‐Matthias Pollok,
Frontiers in Physiology

Abstract

This study shows that c-SRC is inactive in activated myofibroblast-like HSC in liver cirrhosis. Inactivation of c-SRC is mediated by a crosstalk with RhoA upon hepatic stellate cell activation and fibrosis progression.

References

YearCitations

Page 1