Truncation mutants of ASXL1 observed in myeloid malignancies are expressed at detectable protein levels

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

Omar Abdel‐Wahab, Mazhar Adli, Lindsay M. LaFave et al. · Cancer Cell · 2012 · 590 citations · Full text

Life Sciences, Genetics, Molecular Biology +14

Deletion of Asxl1 results in myelodysplasia and severe developmental defects in vivo

Omar Abdel‐Wahab, Jie Gao, Mazhar Adli et al. · The Journal of Experimental Medicine · 2013 · 321 citations · Full text

Life Sciences, Genetics, Hematology +13

ASXL1 mutations identify a high-risk subgroup of older patients with primary cytogenetically normal AML within the ELN Favorable genetic category

Klaus H. Metzeler, Heiko Becker, Kati Maharry et al. · Blood · 2011 · 277 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Prognostic Significance of<i>ASXL1</i>Mutations in Patients With Myelodysplastic Syndromes

Felicitas Thol, Inna Friesen, Frédérik Damm et al. · Journal of Clinical Oncology · 2011 · 275 citations · Full text

Medicine, Hematology, Molecular Genetics +17

Loss of Asxl1 leads to myelodysplastic syndrome–like disease in mice

Jiapeng Wang, Zhaomin Li, Yongzheng He et al. · Blood · 2013 · 178 citations · Full text

Life Sciences, Genetics, Molecular Genetics +3