First trimester combined screening test in pregnancies derived from blastocyst transfer

Fetal nuchal translucency: ultrasound screening for chromosomal defects in first trimester of pregnancy.

K. H. Nicolaides, G.B. Azar, Dominic Byrne et al. · BMJ · 1992 · 1.1K citations · Full text

Medicine, Genetics, Obstetrics +17

A screening program for trisomy 21 at 10–14 weeks using fetal nuchal translucency, maternal serum free β‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐A

Kevin Spencer, Vivienne Souter, Natasha Tul et al. · Ultrasound in Obstetrics and Gynecology · 1999 · 571 citations

Medicine, Maternal Health, Obstetrics +17

Defects and syndromes in chromosomally normal fetuses with increased nuchal translucency thickness at 10–14 weeks of gestation

Athena P. Souka, R. J. M. Snijders, A Novakov et al. · Ultrasound in Obstetrics and Gynecology · 1998 · 480 citations

Life Sciences, Genetics, Obstetrics +13

First‐trimester screening for trisomy 21 by free beta‐human chorionic gonadotropin and pregnancy‐associated plasma protein‐A: impact of maternal and pregnancy characteristics

Karl Oliver Kagan, D. Wright, Kevin Spencer et al. · Ultrasound in Obstetrics and Gynecology · 2008 · 291 citations · Full text

Medicine, Maternal Health, Obstetrics +15

Pregnancies conceived using assisted reproductive technologies (ART) have low levels of pregnancy-associated plasma protein-A (PAPP-A) leading to a high rate of false-positive results in first trimester screening for Down syndrome

David J. Amor, Juanjuan Xu, J. Halliday et al. · Human Reproduction · 2009 · 177 citations

Medicine, Gynecology, Obstetrics +15