A progesterone-dependent immunomodulatory protein alters the Th1Th2 balance

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes.

René de Waal Malefyt, J S Abrams, B Bennett et al. · The Journal of Experimental Medicine · 1991 · 3.8K citations · Full text

Life Sciences, Immunology, Immunoregulation +10

Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones.

David Fiorentino, M W Bond, Timothy R. Mosmann · The Journal of Experimental Medicine · 1989 · 2.7K citations

Life Sciences, Cell Biology, Immunology +17

Two types of mouse helper T cell clone. III. Further differences in lymphokine synthesis between Th1 and Th2 clones revealed by RNA hybridization, functionally monospecific bioassays, and monoclonal antibodies.

Holly Cherwinski, J H Schumacher, Kenneth D. Brown et al. · The Journal of Experimental Medicine · 1987 · 1K citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Synthesis of T helper 2-type cytokines at the maternal-fetal interface.

Hui-An Lin, Timothy R. Mosmann, L.J. Guilbert et al. · The Journal of Immunology · 1993 · 906 citations

Life Sciences, Immunology, Cellular Immunology +16

Anti-proliferative effect of IFN-gamma in immune regulation. I. IFN-gamma inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones.

Thomas F. Gajewski, F W Fitch · The Journal of Immunology · 1988 · 838 citations · Full text

Life Sciences, Cell Biology, Immunology +14