Studies on the Chemical Constituents of Rutaceous Plants. XLIV. The Chemical Constituents of Xanthoxylum integrifoliolum (MERR.) MERR. (Fagara integrifoliola MERR.) (1) The Chemical Constituents of the Root Wood

Abstract

Chemical constituents of the root wood of X. integrifoliolum (MERR.) MERR. (F. integrifoliola MERR.), Rutaceae, were examined. Two new alkaloids, integriamide (25), mp 302-304°C, and integriquinolone (43), mp 257-260°C, were isolated with ten known alkaloids [Dictamnine (7), skimmianine (11), 4-methoxy-1-methyl-2-quinolone (12), arnottianamide (13), haplopine (14), rutaecarpine (16), (+)-platydesmine (29), myrtopsine (30), α-allocryptopine (32), and robustine (33)]. Other than alkaloids four known coumarins [6, 7, 8-trimethoxycoumarin (8), 5, 6, 7-trimethoxycoumarin (9), aesculetin dimethyl ether (10), and fraxinol (19)], and six known components [acid mixture, lupeol (5), β-sitosterol (6), d-sesamin (15), dl-syringaresinol (34), and 2, 6-dimethoxy-p-benzoquinone (35)], were isolated.