PubMed · 1998 · 57 citations · 0 references
Natural SciencesChemistryMicrobiologyDiagnostic MicrobiologySpectroscopic AnalysisSpectroscopyAbsorption SpectroscopyInfrared SpectroscopyOptical SpectroscopyPathogen DetectionBacterial Resistance DetectionCluster AnalysisHigh-throughput Strain ScreeningInfrared Absorption SpectraInfrared Absorption SpectroscopyInfrared SpectraInfrared Spectroscopic AnalysisRapid Screening Tests
Statistical methods such as principal component analysis and cluster analysis were used to analyze ATR-FT-IR spectra obtained from bacterial whole cells. Both methods gave satisfactory results and are conclusive in showing that they can discriminate and classify bacterial strains of clinical origin exhibiting different resistance mechanisms. This approach places FT-IR spectroscopy at the forefront of those new potential techniques that could be used in the rapid screening of microorganisms.