Chemical Communications · 2015 · 99 citations · 30 references
Life SciencesCell BiologyMolecular BiologyBiosensorsGene ExpressionMolecular OncologyCancer Molecular DiagnosticsCell-based BiosensorsCellular ProbesMessenger Rna BiosensorsMolecular Beacon AmplificationMolecular BeaconsRna Biosensors
Due to its low cytotoxicity, high resistance to enzymatic degradation, and cellular permeability, a DNA tetrahedron-based molecular beacon (DTMB) is designed for tumor-related TK1 mRNA detection in living cells, where the target sequence can induce the tetrahedron from contraction to extension, resulting in fluorescence restoration.
30
Folding DNA to create nanoscale shapes and patterns
Paul W. K. Rothemund · Nature · 2006 · 7.4K citations
Quantification of mRNA using real-time RT-PCR
Tania Nolan, Rebecca Hands, Stephen A. Bustin · Nature Protocols · 2006 · 2.3K citations