Stable Production of Human Insulin-like Growth Factor 1 (IGF-1) in the Milk of Hemi- and Homozygous Transgenic Rabbits Over Several Generations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Analytical Biochemistry · 1987 · 63.2K citations

Nucleic Acid Chemistry, Engineering, Natural Sciences +7

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

Piotr Chomczyński, Nicoletta Sacchi · Analytical Biochemistry · 1987 · 46.8K citations

Engineering, Natural Sciences, Rna Isolation +7

Cloned Transgenic Calves Produced from Nonquiescent Fetal Fibroblasts

José B. Cibelli, Steven L. Stice, Paul J. Golueke et al. · Science · 1998 · 1.4K citations

Regenerative Medicine, Marker Gene, Animal Reproduction +14

Human Factor IX Transgenic Sheep Produced by Transfer of Nuclei from Transfected Fetal Fibroblasts

Angelika Schnieke, Alexander Kind, William A. Ritchie et al. · Science · 1997 · 903 citations

Oocyte, Factor Ix, Marker Gene +15

Repeat-induced gene silencing in mammals

David Garrick, Steven Fiering, David I. K. Martin et al. · Nature Genetics · 1998 · 897 citations

Knockout Mouse, Genetics, Genomic Mechanism +5