Hepatic eosinophil granulocytopoiesis in murine experimental Schistosomiasis mansoni.

Abstract

In livers of mice with acute schistosomiasis eosinophil granulocytopoietic folliculi are described. Exogen stem cells were observed in hepatic sinusoids. Their proliferation and progressive maturation are described. Specific reactions to the presence of worms and their eggs, and Kupffer-cell stimulation and hyperplasia are considered to be responsible for this extramedullary granulocytopoiesis.